Scientific Program

NeuroTrauma 2018 has been accreditated through VCU Health Continuing Medical Education!

 

This activity has been planned and implemented in accordance with the accreditation requirements and policies of the Accreditation Council for Continuing Medical Education (ACCME) through the joint providership of VCU Health Continuing Medical Education and International Conference Services, Ltd.

VCU Health Continuing Medical Education is accredited by the ACCME to provide continuing medical education for physicians. VCU Health Continuing Medical Education designates this live activity for a maximum of 37.5 AMA PRA Category 1 Credits™. Physicians should claim only the credit commensurate with the extent of their participation in the activity.

Onsite Program PDF

Abstract Book

Disclosure

*The Scientific Program is subject to change.

SaturdayAugust 11, 2018

  • 07:00 - 19:00

    PSC1 - Pre-Symposium Course: State of the Art on Clinical Management of Brain and Spine Trauma

    Location: Pier 3, Convention Level, Westin Harbour Castle

    Time

    Talk Title

    Faculty

    07:00-07:45 Registration and Coffee Michael G. Fehlings & Geoffrey Manley
    07:45-08:00 PSC1.01: Welcome Remarks and Course Introduction Michael G. Fehlings & Geoffrey Manley
    08:00-08:15 PSC1.02: Welcome from: Global Neuro; AONA, AOSpine and NREF Paul Manson, James Harrop & Shelly Timmons

    Module 1 08:15-12:00

    Traumatic Brain Injury and Cranial Trauma

    Moderator: Geoffrey Manley

    08:15-08:45 PSC1.03: Traumatic Brain Injury and Cranial Trauma John Povlishock
    08:45–09:15 PSC1.04: Clinical Translational Advances in Traumatic Brain Injury Geoffrey Manley
    09:15–09:45 PSC1.05: Advanced Techniques in Cranial Reconstruction Paul Manson
    09:45–10:15 PSC1.06: Decompressive Craniectomy Peter Hutchinson

    10:15-13:30

    Coffee and Networking Break

    10:30–11:00 PSC1.08: Critical Care of Traumatic Brain Injury in Adults and Children Andrew Baker & Jamie Hutchinson
    11:00–11:30 PSC1.09: Management of Traumatic Brain Injury in Children Anthony Figaji
    11:30–12:30 PSC1.10: Traumatic Brain Injury and Cranial Trauma Shelly Timmons

    12:30-12:45

    Networking Break and Pick Up of Boxed Lunch

    12:45–13:30 PSC1.12: Luncheon Seminars - An International Perspective on Traumatic Brain Injury - Biomarkers for Spinal Cord Injury - Discussion Andrew Maas & Brian Kwon

    Module 2 13:30-17:30

    Spine Trauma and Spinal Cord Injury

    Moderator: Michael G. Fehlings

    13:30–14:00 PSC1.13: Spine Trauma and Spinal Cord Injury Dalton Dietrich
    14:00–14:30 PSC1.14: Clinical Translational advances in Spinal Cord Injury Michael G. Fehlings
    14:30–15:00 PSC1.15: Assessment & Management of Spinal Cord Injury James Harrop
    15:00–15:30 PSC1.16: Critical Management of Spinal Cord Injury (including review of the AO Spine Guidelines) Greg Hawryluk

    15:30-15:45

    Coffee and Networking Break

    15:45–16:30 PSC1.18: Panel: Role and Timing of Surgery in Spinal Cord Injury Moderator: Michael Fehlings Michael G. Fehlings Bizhan Aarabi James Harrop Eve C. Tsai Brain Kwon Jefferson Wilson Mark Kotter Shekar Kurpad
    16:30–17:30 PSC1.19: Panel: Management of Complex Thoracolumbar Spine Trauma Moderator: James Harrop James Harrop Jefferson Wilson Bizhan Aarabi Brian Kwon Eve C. Tsai Mark Kotter David Okonkwo

    17:30-19:00

    Networking Cocktail Reception

SundayAugust 12, 2018

  • 07:30 - 16:30

    PSC2 - AANS/CNS Pre-Symposium Course: Debates in Neurotrauma - Treatment of Brain and Spinal Cord Injury

    Location: Pier 4+5, Convention Level, Westin Harbour Castle Hotel

    Proposed Program

    Time

    Talk Title

    Faculty

    07:30 AANS/ CNS Breakfast
    Neurotrauma History and Guidelines Updates  Moderator: Eve C. Tsai
    08:30 PSC2.01: Brain Injury Guidelines History and Update David Onkonkwo
    08:50 PSC2.02: Neurotrauma History and Guidelines Updates Charles Tator
    09:10 PSC2.03: Neurotrauma History and Guidelines Updates Michael G. Fehlings
    09:30 PSC2.04: Pediatric Trauma History and Guidelines Update David Adelson
    09:50 PSC2.05: Questions
    10:00 Coffee Break
    Should ICP Monitoring be Continued? Moderator: Alan Hoffer
    10:30 PSC2.07: Case Presentation - Patient with Bifrontal Confusions, No Signification Hemorrhagic Lesion Alan Hoffer
    10:35 PSC2.08: Pro Greg Hawryluk
    10:45 PSC2.09: Con Dan Michael
    10:55 PSC2.10: Discussion and Verdict
    Surgical Treatment of Elderly with Odontoid Fracture  Moderator: Alan Hoffer
    11:00 PSC2.11: Case Presentation Jamie Wilson
    11:05 PSC2.12: Pro Jeff Wilson
    11:15 PSC2.13: Con James Harrop
    11:25 PSC2.14: Discussion and Verdict
    Stem Cells for Clinical Neural Repair: Ready for Prime Time? Moderator: Alan Hoffer
    11:30 PSC2.15: Case Presentation - Patient with Spinal Cord Injury and Cystic Cavity Stephanie de Vere
    11:35 PSC2.16: Pro Ann Parr
    11:45 PSC2.17: Con Eve C. Tsai
    11:55 PSC2.18: Discussion and Verdict
     12:00  Lunch
    Cutting Edge Trauma Management of Brain and Spinal Injuries Moderator: Tuan Bui
    13:00 PSC2.20: Military Management of Brain and Spinal Injuries Christopher Neil
    13:20 PSC2.21: Intraspinal Monitoring and Dural Decompression for Spinal Cord Injury Marios Papadopoulous
    13:40 PSC2.22: Anticoagulation and Trauma Suzanne Tharin
    14:00 PSC2.23: Machine Learning to Improve Neurosurgery Uzma Samadani
    14:20 Questions
    14:40 AANS/ CNS Coffee Break
    Chronic Subdural Hematoma and Steroids Moderator: Fahad Alkherayf
    15:00 PSC2.24: Case Presentation Kevin Kwan
    15:05 PSC2.25: Pro Roxanne Todor
    15:15 PSC2.26: Con Jamie Ullman
    15:25 PSC2.27: Discussion and Verdict Kevin Kwan
    Management of a Thoracolumbar Burst Fracture Moderator: Fahad Alkherayf
    15:30 PSC2.28: Case Presentation - Patient with Burst Fracture, Neurologically Intact Mohammed Alswat
    15:35 PSC2.29: Nonsurgical Brian Kwon
    15:45 PSC2.30: Surgical Paul Arnold
    15:55 PSC2.31: Discussion and Verdict Mohammed Alswat
    Is Decompressive Craniotomy Beneficial? Moderator: Fahad Alkherayf
    16:00 PSC2.32: Case Presentation Ziyad Makoshi
    16:05 PSC2.33: Pro Peter Hutchison
    16:15 PSC2.34: Con Shelly Timmons
    16:25 PSC2.35: Discussion and Verdict Ziyad Makoshi
  • 12:00 - 13:00

    TEAM Business Meeting

    Location: Pier 3, Lower Level, Conference Centre, Westin Harbour Castle Hotel
    TEAM logo
  • 12:00 - 13:00

    LS1 - Lunch Symposium - Advanced Monitoring in the Neuro ICU

    Location: Pier 4, Convention Level, Westin Harbour Castle
    Click here for further details.

    Supported by Codman Specialty Surgical

    Codman-Specialty-Surgical_web
  • 14:00 - 16:00

    TEAM Council Meeting

    Location: Yonge, Lower Level, Conference Centre, Westin Harbour Castle
    TEAM logo
  • 16:30 - 18:00

    NNS Council Meeting

    Location: Yonge, Lower Level, Conference Centre, Westin Harbour Castle
    NNS-Society Logo OFFICIAL
  • 18:30 - 20:00

    NeuroTrauma 2018 Welcome Reception

    Location: Harbour Ballroom Foyer + Terrace, Convention Level, Westin Harbour Castle
    Join us for the Welcome Reception and to mix and mingle with sponsors & exhibitors, colleagues and friends while enjoying local wines, beers and small snacks.

    *Included in the registration fee for delegates.

    supported by

    Mission Connect_logo_web-01

MondayAugust 13, 2018

  • 07:00 - 08:00

    NNS Business Meeting

    Location: Bay, Lower Level, Conference Centre, Westin Harbour Castle
    NNS-Society Logo OFFICIAL
  • 07:30 - 08:20

    BS1 - Breakfast Symposium: Direct cell reprogramming technology and its potential in the treatment of Neurotrauma

    Location: Pier 2, Convention Level, Westin Harbour Castle
    Click here for further details.

    Supported by Fortuna Fix

    Fortuna-Fix_web  
  • 08:30 - 10:45

    P1 - Plenary Session: State of the Art in Neurotrauma: From Cell to Community

    Location: Frontenac Ballroom, Lower Level, Conference Centre, Westin Harbour Castle
    Chair: Michael G. Fehlings, Canada
    • P1.01: Repair and Regeneration of the Injured Spinal Cord: Clinical Translation Advances - Michael G. Fehlings, Canada
    • P1.02: Rescuing the Injured Brain - Peter Hutchinson, United Kingdom
    • P1.03: Recent advances in protection and repair after Spinal Cord Injury - Dalton Dietrich, United States
    • P1.04: Evidence for Neocortical Circuit Disruption following Mild Traumatic Brain Injury - John T. Povlishock, United States
  • 10:45 - 11:15

    Poster Session, Coffee Break and Exhibits

    Location: Metropolitan Ballroom, 2nd Level, Conference Centre, Westin Harbour Castle
    Refreshments supported by

    L&K BIOMED

  • 11:15 - 12:45

    S1 - Scientific Session: Outcomes Assessment in TBI and SCI

    Location: Harbour Ballroom A+B, Convention Level, Westin Harbour Castle
    Chair: Andrew Maas, Belgium
    • S1.01: Approaches to outcome assessment in TBI: Challenges and opportunities - Andrew Maas, Belgium
    • S1.02: Outcome after TBI across Europe - Nicole von Steinbüchel, Germany
    • S1.03: Sensitive Assessment after Traumatic Tetraplegia with a focus on the Upper Limb: Do we Really Understand the Natural History of Disease? - Sukhvinder Kalsi-Ryan, Canada
    • S1.04: Outcomes and prediction in acute spinal cord injury - Armin Curt, Switzerland
  • 11:15 - 12:45

    S2 - Scientific Session: Electrical Stimulation and Repair in SCI

    Location: Harbour Ballroom C, Convention Level, Westin Harbour Castle
    Chair: Susan Harkema, United States
    • S2.01: Functional Electrical Stimulation Therapy for Improving Voluntary Grasping Function Following SCI - Milos Popovic, Canada
    • S2.02: A continuum of strategies for neuroplasticity and recovery using epidural stimulation after spinal cord injury - Susan Harkema, United States
    • S2.03: Activation of Spinal Networks for Improving Mobility after Spinal Cord Injury - Vivian Mushawar, Canada
  • 11:15 - 12:45

    S3 - Scientific Session: Major Ongoing Studies in TBI

    Location: Pier 2+3, Convention Level, Westin Harbour Castle
    Chair: David Okonkwo, United States
    • S3.01: Michael J. Bell, United States
    • S3.02: TEAM-TBI: Targeted Evaluation, Action and Monitoring of Traumatic Brain Injury - David Okonkwo, United States
    • S3.03: Track-TBI - Geoffery Manley, United States
    • S3.04: Andrew Maas, United States
  • 13:00 - 14:00

    LS2 - Lunch Symposium: NINDS Strategies to Enhance Diversity of Neuroscience Researchers

    Location: Pier 2+3, Convention Level, Westin Harbour Castle
    Click here for further details.

    Supported by:

    TEAM logo
  • 14:15 - 16:00

    P2 - Plenary Session: Acute and Chronic Stress After Central Nervous System Injury

    Location: Frontenac Ballroom, Lower Level, Conference Centre, Westin Harbour Castle
    Chairs: David Morilak, United States &, Patricia de la Tremblaye, United States
    • P2.01: Stress-related cognitive impairment and therapeutic response may influence the course of decline and recovery from TBI - David Morilak, United States
    • P2.02: Interaction of brain trauma and chronic unpredictable stress on cognition, anxiety, and markers of neurotransmission and neuroinflammation - Corina Bondi, United States
    • P2.03: Early life stress increases vulnerability to experimental brain injury - Naima Lajud Avila, Mexico
    • P2.04:  Chronic outcomes in a mouse model of repeated, unpredictable stress - Fiona Crawford, United States
  • 16:00 - 16:30

    Poster Session, Coffee Break and Exhibits

    Location: Metropolitan Ballroom, 2nd Level, Conference Centre, Westin Harbour Castle
  • 16:30 - 18:00

    S4 - Scientific Session: Dietary Fat in CNS Trauma and Repair

    Location: Harbour Ballroom A+B , Convention Level, Westin Harbour Castle
    Chair: Isobel A. Scarisbrick, United States
    • S4.01: Ketogenic diet for acute spinal cord injury - Wolfram Tetzlaff, Canada
    • S4.02: Metabolic Links Between Exercise and Dietary Fat Regulate Myelin in the Adult CNS: Implications for Recovery after SCI - Isobel A. Scarisbrick, United States
    • S4.03: Axon-myelin Interactions in Traumatic White Matter Injury - Regina Armstrong, United States
    • S4.04: The interplay between brain and gut in the pathophysiology of brain trauma - Fernando Gomez-Pinilla, United States
  • 16:30 - 18:00

    S5 - Scientific Session: Modulators of Tissue Scarring and Extracellular Matrix

    Location: Harbour Ballroom C, Convention Level, Westin Harbour Castle
    Chair: Jerry Silver, United States
    • S5.01: Rapid and robust recovery of breathing long after spinal cord injury  - Jerry Silver, United States
    • S5.02: Rescuing the Fate of Neural Progenitor Transplants in Spinal Cord Injury Niche via Attenuation of Notch Signaling with GDNF - Mohamad Khazaei, Canada
    • S5.03: Directly reprogrammed human oligodendrogenic neural progenitor cells delivered with chondroitinase ABC facilitate functional repair of chronic spinal cord injury - Satoshi Nori, Japan
    • S5.04: Enhancing plasticity for functional recovery after spinal cord injury - Jessica Kwok, United Kingdom
  • 16:30 - 18:00

    S6 - Scientific Session: The International TBI Initiative

    Location: Pier 2+3, Convention Level, Westin Harbour Castle
    Chair: Ramona Hicks, United States
    • S6.01: The International TBI Research Initiative - Five Years On! - Ramona Hicks, United States
    • S6.02: Historical and Future Perspectives on InTBIR - Andrew Maas, United States
    • S6.03: Neuroimaging Biomarkers: The power of standardization and collaboration  - Stephan Strother, Canada
    • S6.04: Genomics and Proteomics: The power of standardization and collaboration - Ramon Diaz-Arrastia, United States
    • S6.05: Translating Knowledge to Practice:  Scenarios for Sustained International Cooperation in TBI Research - Elizabeth Theriault
  • 18:00 - 19:00

    PM1 - Poster Mixer 1

    Location: Metropolitan Ballroom, 2nd Level, Conference Centre, Westin Harbour Castle
    Join our Poster Mixers and discuss the latest research and innovations with your fellow colleagues and friends. Enjoy a drink and small snacks while networking.

TuesdayAugust 14, 2018

  • 07:30 - 08:20

    BS2 - Breakfast Symposium: ERA-NET Neuron – European interdisciplinary multi-site studies for Translational Research in Traumatic Brain Injury

    Location: Pier 2+3, Convention Level, Westin Harbour Castle
    Click here for further details.

    Supported by

    European Neurotrauma Network_Logo
  • 08:30 - 10:15

    P3 - Plenary Session: Advances in CNS Regeneration and Plasticity

    Location: Frontenac Ballroom, Lower Level, Conference Centre, Westin Harbour Castle Hotel
    Simone Di Giovanni, United Kingdom
    • P3.01: - Samuel David
    • P3.02 Injury dependent and independent signalling for the control of axonal regeneration - Simone di Giovanni, United Kingdom
    • P3.03: Biomaterial bridge-mediated facilitation of axonal regeneration and recovery in acute and chronic spinal cord injury - Aileen Anderson, United States
    • P3.04: RGMa neutralization promotes functional recovery following spinal cord injury - Philippe Monnier, Canada
    • P3.05: dI3 interneurons: a target for neuroplasticity and regeneration for recovery of locomotor function - Tuan Bui, Canada
  • 10:15 - 11:15

    Poster Session, Coffee Break and Exhibits

    Location: Metropolitan Ballroom, 2nd Level, Conference Centre, Westin Harbour Castle
  • 11:15 - 12:45

    S7 - Scientific Session: Clinical Biomarkers and Trials for TBI and SCI

    Location: Harbour Ballroom A+B, Convention Level, Westin Harbour Castle
    Chair: Brian Kwon, Canada
    • S7.01: An update on Diagnostic and Prognostic Biomarkers for Traumatic Brain injury - Kevin K.W. Wang, United States
    • S7.02: Biomarkers of Acute Spinal Cord Injury - Brian Kwon, Canada
    • S7.03: MicroRNA Biomarkers Predict Degenerative Cervical Myelopathy Severity and Surgical Outcome - Alex Laliberte, Canada
    • S7.04: Moving from Estimates to Clinical Impact: a Systematic Analysis of the Use of Blood-based Biomarkers in the Field of Traumatic Brain Injury - Stefania Mondello, Italy
  • 11:15 - 12:45

    S8 - Scientific Session: Inflammation and its Role in Injury/Recovery

    Location: Harbour Ballroom C, Convention Level, Westin Harbour Castle
    Chair: Alan Faden, United States
    • S8.01: New immunomodulatory targets for spinal cord injury - Soheila Karimi, Canada
    • S8.02: Sustained Neuroinflammation and Progressive Neurodegeneration after TBI or SCI: Mechanisms and Modulation - Alan Faden, United States
    • S8.03: Age-dependent neuroinflammation: The role of macrophages in SCI recovery - John Gensel, United States
    • S8.04: Matrix metalloproteinases and Spinal Cord Injury: Deciphering their complex roles in neurological and urological recovery - Linda Noble-Haeusslein, United States
  • 11:15 - 12:45

    DB1 - Open Communication Data Blitz

    Location: Pier 2+3, Convention Level, Westin Harbour Castle
    Chair: Bevan Main, United States
    • DB1.01.01: Direct Comparison of Adult Human and Rat Spinal Cord Stem/Progenitor cell Response to Inflammatory and Regenerative Cues - Ahmad Galuta, Canada
    • DB1.02.01: Molecular Pain Targets In Rodent and Human Spinal Cord: Implications for Translation of Novel Therapies for Traumatic Pain - Chaya Kandegedara, Canada
    • DB1.03.01: AMPA Receptor Modulation as a Therapeutic Strategy to Enhance Survival of Spinal Cord Neural Stem Cells - Laureen Hachem, Canada
    • DB1.03.02: IP3R-mediated intra-axonal Ca2+ release contributes to secondary axonal degeneration following contusive SCI - Nicolas Pelisch, United States
    • DB1.03.03: Naltrexone amplifies disruption in locomotor function following hindlimb stretching in rats with spinal cord injuries - Gregory States, United States
    • DB1.03.04: Regional and Institutional Practice Variations in Penetrating Spinal Cord Injury in the United States - Pranay Soni, United States
    • DB1.03.05: Oligogenic Directly Reprogrammed NPCs Combine with Affinity-Release ChABC to Regenerate the Chronically Injured Spinal Cord - Christopher Ahuja, Canada
    • DB1.04.01: DNA damage induces early brain aging after traumatic brain injury - Nicole Schwab, Canada
    • DB1.04.02: A New Class of Carbon Antioxidants Restored Cerebral Perfusion in Traumatic Brain Injury Complicated by Systemic Hypotension - Kimberly Mendoza, United States
    • DB1.04.03: ENIGMA Military Brain Injury: Framework and Preliminary dMRI Meta-analysis - Emily Dennis, United States
    • DB1.04.04: Effects of pituitary function on long-term health outcomes following mTBI in service members treated at the CRCC - Stephanie Ciarlone, United States
    • DB1.04.05: CLARITY reveals less disconnection of axons than previously thought and a more prolonged process of degeneration after TBI - Maura Weber, United States
    • DB1.04.06: Characterization of EPO/EPOr expression and activation before and after TBI with delayed hypoxemia - Marta Celorrio, United States
    • DB1.04.07: High-G head collisions are associated with short-term white matter microstructural deficits in high school football athletes - Yukai Zou, United States
    • DB1.04.08: Inhibition of TLR4 with C34 attenuates the neuroinflammatory response to traumatic brain injury - Young Chun, United States
    • DB1.04.09: Acute mitochondrial impairment underlies prolonged cellular dysfunction after repeated mild traumatic brain injuries - William Hubbard, United States
    • DB1.04.10: GABAergic synapse degeneration after mild traumatic brain injury in mice - Michal Vascak, United States
    • DB1.04.11: Sex differences in acute neurodegeneration and sustained impairment of axonal function following diffuse TBI in mice - Jennifer Creed, United States
  • 13:00 - 14:00

    LS3 - Lunch Symposium: Update on AOSPine Guidelines for Traumatic SCI

    Location: Harbour Ballroom A+B, Convention Level, Westin Harbour Castle
    Click here for further details.

    Supported by:

    AOSpineKnowledgeForum_webAOSpine_International Logo
  • 15:30 - 18:00

    Chinese Neurotrauma Scholar Association (CNSA): The 8th Annual MiniSymposium

    Location: Pier 2+3, Convention Level, West Harbour Castle
    Theme: Global Trends in Translational Neurotrauma Research
    3:30 - 5:30 pm Scientific Program:
    3:30 - 3:35 pm Welcome remark (Ping Wu) Introduction of speakers (Shuxin Li & Dong Sun)
     3:35 – 4:05 pm Prof. Bing Song, Cardiff Univ., UK “Electrical signals in controlling cell migration and stem cell behavior for SCI”
    4:05 – 4:35 pm Prof. Wai S. Poon,   潘偉生 Chinese University of Hong Kong, Hong Kong “Translational cell-based therapies from animal models to human TBI and SCI: Practical considerations”
    4:35 – 5:05 pm Prof. Baiyun Liu, 刘佰运 Tiantan Hospital, Beijing, China “Chinese Technical Guidelines for Large Decompressive Craniectomy in Adult Patients with Severe Traumatic Brain Injury”
    5:05 – 5:35 pm Dr. Jason Huang, M.D., Baylor Scott & White Health in Temple, TX. “Management of Blast-Related Traumatic Brain Injury with a Review of Combat    Neurosurgical Experience”
    5:35 – 5:40 Closing remark (Kevin Wang & Xiaoming Xu)
    5:40 – 6:00 CNSA Business Meeting  (Ping Wu)
    6:30 pm CNSA Networking Dinner  (all are welcome, pay on your own)
     
  • 18:30 - 21:00

    CNSA Group Dinner (everyone is welcome)

    Location: Pearl Harbourfront Chinese Cuisine, 2nd Floor, 200-207 Queens Quay W

WednesdayAugust 15, 2018

  • 08:30 - 10:15

    P4 - Plenary Session: Advanced/Multimodal Imaging in Injury Diagnosis for SCI and TBI

    Location: Frontenac Ballroom, Lower Level, Conference Centre, Westin Harbour Castle
    Chair: Virginia Newcombe, United Kingdom
    • P4.01: Standardization of acquisition and data processing in spinal cord MRI: Application in degenerative cervical myelopathy - Julien Cohen-Adad, Canada
    • P4.02: Advanced imaging methods: what is on the horizon? - Claudia Wheeler-Kingshott, United Kingdom
    • P4.03: Advanced imaging methods: what is on the horizon? - David Menon, United Kingdom
    • P4.04: Early MRI after TBI: more than an image - Virginia Newcombe, United Kingdom
  • 10:15 - 11:15

    Poster Session, Coffee Break and Exhibits

    Location: Metropolitan Ballroom, 2nd Level, Conference Centre, Westin Harbour Castle
  • 11:15 - 12:45

    S9 - Scientific Session: Cell Replacement in SCI and TBI

    Location: Harbour Ballroom A+B, Convention Level, Westin Harbour Castle
    Chair:Mark Kotter, United Kingdom
    • S9.01: Cell transplantation for Spinal Cord Injury - an overview of clinical Trials - Mark Kotter, United Kingdom
    • S9.02: Mesenchymal stem cells in a nanofiber-hydrogel composite matrix for spinal cord repair - Martin Oudega, United States
    • S9.03: Stimulating endogenous neural precursors to promote self repair of the injured CNS - Cindi Morshead, Canada
    • S9.04: Application of human neural precursor cells for spinal cord injury – from bench to bedside - Narihito Nagoshi, Japan
  • 11:15 - 12:45

    S10 - Scientific Session: Preclinical Models of Neurorehabilitation for TBI

    Location: Harbour Ballroom C, Convention Level, Westin Harbour Castle
    Chair: Corina Bondi, United States
    • S10.01: Does Brain Stimulation Enhance Rehabilitation Efficacy after TBI? - DeAnna L. Adkins, United States
    • S10.02: Grace Griesbach, United States
    • S10.03: Optimizing environmental enrichment to model preclinical neurorehabilitation - Jeffrey Cheng, United States
    • S10.04: Neural Plasticity and Neurorehabilitation following TBI in the Rat: Translation to the Clinic? - Dorothy Kozlowski, United States
  • 11:15 - 12:45

    DB2 - Open Communication Data Blitz

    Location: Pier 2+3, Convention Level, Westin Harbour Castle
    Chair: Chris Ahuja, Canada
    • DB2.03.01: Projection specific mechanisms of auditory sensitivity that contribute to enhanced fear after TBI - Ann Hoffman, United States
    • DB2.03.02: 5-HT1f receptor agonists induce mitochondrial biogenesis and promote recovery from spinal cord injury - Epiphani Simmons, United States
    • DB2.03.03: Pathological patterns of spinal cord blood flow after injury visualised with laser speckle contrast imaging - Mathew Gallagher, United Kingdom
    • DB2.03.04: Drug Re-purposing: High Dose Human Immunoglobulin G for Treatment of Traumatic Cervical Spinal Cord Injury - Jonathan Chio, Canada
    • DB2.03.05: MIS416 enhances recovery from traumatic spinal cord injury (SCI) in mice by regulating the innate immune response - Masoud Hassanpour Golakani, Australia
    • DB2.04.01: Associations of Head Injury with Risk of Mortality, Incident Coronary Heart Disease, Stroke, and Heart Failure - Andrea Schneider, United States
    • DB2.04.02: Sensory Hypersensitivities in Patients with Persistent Post-Traumatic Headache vs. Migraine - Jeffery Hanna, United States
    • DB2.04.03: Cognitive training improves neural efficiency in TBI - Kihwan Han, United States
    • DB2.04.04: Investigating the Neurological Effects of Sleep Deprivation on Post Concussion Symptomology in Adolescent Rats - Sabrina Salberg, Canada
    • DB2.04.05: Traumatic brain injury-induced neuronal damage induces cortical rod microglia that promote persistent neuroinflammation - Kristina Witcher, United States
    • DB2.04.06: Prognostic inflammatory biomarkers for traumatic brain injury: A TRACK-TBI Pilot Study - Margalit Haber, United States
    • DB2.04.07: Individualized brain network architecture distinguishes TBI-associated depression from TBI, major depression, and PTSD - Shan Siddiqi, United States
    • DB2.04.08: Catastrophic disruption of the blood-brain barrier in pediatric TBI - Josie Fullerton, UK
    • DB2.04.09: Reprogramming Monocyte-Derived Macrophages to Mitigate Secondary Injury Pathology Following Traumatic Brain Injury - Kathryn Wofford, United States
    • DB2.04.10: Diagnostic utility of GFAP for identifying TBI patients with MRI abnormalities despite normal head CT: A TRACK-TBI study - John Yue, United States
    • DB2.04.11: Repetitive Transcranial Magnetic Stimulation with Resting State Network Targeting for Treatment-Resistant Depression in TBI - Shan Siddiqi, United States
    • DB2.04.12: Variation in Structure and Process of Care in Traumatic Brain Injury:  Provider Profiles in the CENTER-TBI Study - Maryse Cnossen, Netherlands
    • DB2.04.13: Temporal lobe contusions are associated with impaired six-month functional recovery after mild TBI: A TRACK-TBI study - John  Yue, United States
    • DB2.04.14: Multimodal assessment of behavioral flexibility after frontal brain trauma: beneficial effects of milnacipran - Timothy Craine, United States
    • DB2.04.15: Three-dimensional interrogation of traumatic axonopathy in the brain identifies SARM1 as major driver of axonal degeneration - Nikolaos Ziogas, United States
    • DB2.04.16: Sleep-wake cycle deregulation despite normal circadian clock signal in acute traumatic brain injury - Catherine Duclos, Canada
    • DB2.04.17: Evaluation and evolution of the olfactory system within the first 24 hours after a mild traumatic brain injury (mTBI). - Fanny Lecuyer Giguere, Canada
    • DB2.04.18: Modeling of Traumatic Brain Injury (TBI) due to Head Impacts with Unmanned Aircraft Systems (UAS) - Anna Marie Dulaney, United States
  • 13:00 - 14:00

    LS4 - Lunch Symposium: Research, Innovation and Translation in SCI

    Location: Pier 2+3, Convention Level, Westin Harbour Castle
    Click here for further details.

    Supported by

    ONF_web Rick Hansen
  • 14:15 - 16:00

    P5 - Plenary Session: Advances in Neurorehabilitation: Bench to Bedside

    Location: Frontenac Ballroom, Lower Level, Conference Centre, Westin Harbour Castle
    Chair: Ross Zafonte, United States
    • P5.01: Control of Reaching and Grasping following SCI - Monica Perez, United States
    • P5.02: The placebo response: the role of the rouse in rehabilitation - Ross Zafonte, United States
    • P5.03: Neural control of locomotor outcomes in human SCI - Armin Curt, Switzerland
    • P5.04: Post-Traumatic Epilepsy: Personal Biology, Clinical Predictors, and Disability Burden - Amy Wagner, United States
  • 16:00 - 16:30

    Poster Session, Coffee Break and Exhibits

    Location: Metropolitan Ballroom, 2nd Level, Conference Centre, Westin Harbour Castle
  • 16:30 - 18:00

    S11 - Scientific Session: Neurotrauma Across the Lifespan

    Location: Harbour Ballroom A+B, Convention Level, Westin Harbour Castle
    Chair: Robert Clark, United States
    • S11.01: Robert Clark, United States
    • S11.02: Neuroinflammation: how aging impacts microglial function following acute brain trauma - David Loane, United States
    • S11.02: Frequency-Dependent Changes in Resting State EEG Functional Networks in Piglets after Rapid Head Rotations - Implications for Identifying Mild Brain Injury Across the Lifespan - Susan Margulies, United States
    • S11.03: Progressive neuropathology and the emergence of behavior deficits after pediatric TBI - Bridgette Semple, Australia
    • S11.04: Gut microbiota are disease modifying factors after spinal cord injury - Kristina Kigerl, United States
  • 16:30 - 18:00

    S12 - Scientific Session: Update on Clinical Trials in SCI

    Location: Harbour Ballroom C, Convention Level, Westin Harbour Castle
    Chair: Greg Hawryluk, United States
    • S12.01: Greg, Hawryluk, United States
    • S12.02: Jan Schwab, United States
    • S12.03: Role of Baseline Magnetic Resonance Imaging in Clinical Decision Making and Outcome Prediction (clinical update) - Bizhan Aarabi, United States
    • S12.04: The SPRING Study: A Phase 2b/3 Study of the Efficacy and Safety of VX-210 in Subjects with Acute Cervical Spinal Cord Injury: Study Design, Status, and Baseline Characteristics - Marco Rizzo, United States
    • S12.05: Translation of self-delivering RNA  to silence PTEN  and promote axon regeneration after neurotrauma - Lisa Mckerracher, United States
  • 16:30 - 18:00

    PP1 - Patient Perspective

    Location: Pier 2+3, Convention Level, Westin Harbour Castle
    Chair: Michael G. Fehlings, Canada
    • PP1.01: My Story-Hope - Tara Jeji, Canada
    • PP1.02: Creative Fund Development for SCI Research - Barry Munro, Canada
    • PP1.03: ONF as the Catalyst in Acquired Brain Injury: Working With Providers, Patients and Planners - Corinne Kagan , Canada
  • 18:00 - 19:00

    PM2 - Poster Mixer 2

    Location: Metropolitan Ballroom, 2nd Level, Conference Centre, Westin Harbour Castle
    Join our Poster Mixers and discuss the latest research and innovations with your fellow colleagues and friends. Enjoy a drink and small snacks while networking.
  • 19:30 - 23:00

    NeuroTrauma 2018 Gala & Awards Dinner

    Location: Harbour Ballroom, Foyer & Terrace, Convention Level, Westin Harbour Castle
    Enjoy an evening with your friends and fellow colleagues. Don't miss a cocktail reception accompanied by a jazz quartet followed by a 3-course meal. We will also honor our Award Winners during this festive evening. Last, but not least we would like to invite you to shake a leg to the tones of a rock and pop after dinner.

    *Tickets are not included in the registration fee and have to purchased separately.

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ThursdayAugust 16, 2018

  • 08:30 - 10:15

    P6 - Plenary Session: Challenges in Managing Neurotrauma in the Developing World

    Location: Frontenac Ballroom, Lower Level, Conference Centre, Westin Harbour Castle
    Chair: Anthony Figaji, South Africa
    • P6.01: Challenges in Managing Neurotrauma in the Developing World - Vafa Rahimi-Movaghar, Iran
    • P6.02: Current management and outcome of spinal trauma in Tanzania - Roger Hartl, United States
    • P6.03: Challenges and Opportunities in Managing Neurotrauma in the Developing World - Anthony Figaji, South Africa
    • P6.04: Challenges in Managing Neurotrauma in the Developing World – The Ethiopian Experience - Sarah Woodrow, Canada
  • 10:15 - 11:15

    Poster Session, Coffee Break and Exhibits

    Location: Metropolitan Ballroom, 2nd Level, Conference Centre, Westin Harbour Castle
  • 11:15 - 12:45

    S13 - Scientific Session: Oxidative Stress and CNS Trauma

    Location: Harbour Ballroom A+B, Convention Level, Westin Harbour Castle
    Chair: Edward Hall, United States
    • S13.01: Oxidative Damage is Higher in Hemorrhagic TBIs: Explanation for Selective Benefit of Tirilazad in tSAH Patients - Edward Hall, United States
    • S13.02: Regulatory Role of Thioredoxin in autophagy-apoptosis cross talk  - Eftekhar Eftekharpour, Canada
    • S13.03: Oxidative Lipid Signaling in Neuronal Death Programs in Brain Trauma. - Hülya BayÏr, United States
    • S13.04: Aldehyde-mediated neuropathic pain in CNS trauma - Riyi Shi, United States
  • 11:15 - 12:45

    S14 - Scientific Session: Diagnosis and Management of Concussion/Biomarkers

    Location: Harbour Ballroom C, Convention Level, Westin Harbour Castle
    Chair: Charles Tator, Canada
    • S14.01: Christopher Giza, United States
    • S14.02: Management of the Sequelae of Repetitive Concussions: Second Impact Syndrome and Postconcussion Syndrome - Charles Tator, Canada
    • S14.03: The utility of biomarkers:  From the field to the clinic - Jonathon Oliver, United States
    • S14.04: Delayed effects of multiple concussions and potential biomarkers of chronic traumatic encephalopathy - Carmela Tartaglia, Canada
  • 11:15 - 12:45

    S15 - Scientific Session: Glucose and Insulin in TBI

    Location: Pier 2+3, Convention Level, Westin Harbour Castle
    Chair: Mayumi Prins, United States
    • S15.01: Fueling the TBI Brain - Mayumi Prins, United States
    • S15.02: Non-invasive imaging of brain glucose after TBI - Reed Selwyn, United States
    • S15.03: Intranasal insulin in the treatment of CNS disorders - Kimberly Byrnes, United States
    • S15.04: Insulin Sensitivity after TBI: Implications for Vulnerability to Cerebral Ischemia - Zach Weil, United States
    • S15.05: Glucose metabolism in the injured brain - Antonio Belli, United Kingdom
  • 12:45 - 14:15

    INTS Board Meeting

    Location: Richmond, Lower Level, Conference Centre, Westin Harbour Castle
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  • 13:00 - 14:00

    Late Breaking Abstract Session

    Location: Pier 2+3, Convention Level, Westin Harbour Castle
    Michael G. Fehlings Fehlings, Canada
    • 1.01: Single experimental traumatic brain injury produces progressive chronic histopathological and behavioral deficits up to one year after injury - Xiang Mao, China
    • 1.02: Human Apolipoprotein E Isoforms Differentially Influence Neurite Outgrowth and Regeneration - Rachel S.J. Maggard, United States
    • 1.03: Recurrent traumatic brain injury surveillance using administrative health data: a Bayesian latent class analysis - Oliver Lasry, Canada
    • 1.04: Cervical excitatory neurons restore breathing after high cervical spinal cord injury - Kajana Satkunendrarajah, Canada
    • 1.05: Comparison of rescue strategies for brain tissue oxygen tension crisis and their effect on regional microvascular tissue hypoxic fraction - Ari Ercole, United Kingdom
  • 13:00 - 14:00

    Lunch Break and Exhibits

    Location: Metropolitan Ballroom, 2nd Level, Conference Centre, Westin Harbour Castle
  • 14:15 - 16:00

    P7 - Plenary Session: Perspectives on SCI and TBI Research Going from NeuroTrauma 2018 to the Future

    Location: Frontenac Ballroom, Lower Level, Conference Centre, Westin Harbour Castle
    Chair: Patrick Kochanek, United States
    • P7.01: Prospects for Axonal Recovery and/or Axonal Regeneration after Spinal Cord Injury - Charles Tator, Canada
    • P7.02: What the present informs us of the future of SCI research - reasons to be optimistic - Samuel David, Canada
    • P7.03: Mitochondrial-targeted pharmacotherapeutics and biopharmaceuticals for spinal cord injury - Alexander G. Rabchevsky, United States
    • P7.04: Optimizing the chance for a future therapeutic breakthrough in the golden age of TBI research - Patrick Kochanek, United States
    • P7.05: Recovery Through Manipulation of the Brain's Endogenous Mechanisms - Esther Shohami, Israel
  • 16:00 - 16:30

    Closing & Handover Ceremony

    Location: Frontenac Ballroom, Lower Level, Conference Centre, Westin Harbour Castle
    Join us for the NeuroTrauma 2018 Closing and Handover Ceremony.

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  • 16:30 - 18:00

    S16 - Scientific Session: Drug Discovery and Development to Advance Preclinical to Clinical Translation

    Location: Harbour Ballroom A+B, Convention Level, Westin Harbour Castle
    Chair: Samuel Poloyac, United States
    • S16.01: Moving from Disease Target to Lead Compound:  Examples in 20-HETE Inhibitor Drug Development - Samuel Poloyac, United States
    • S16.02: Pharmacokinetic modeling and neurometabolomics to ensure target engagement - Philip Empey, United States
    • S16.03: Using Brain Injury Biomarkers to Indentify Potential Drug Targets. - Gretchen Brophy, United States
    • S16.04: Interspecies scaling and Dose optimization: Challenges with Minocycline in acute stroke - Dave Edwards, Canada
  • 16:30 - 18:00

    S17 - Scientific Session: Bioengineering Strategies for Acute SCI

    Location: Harbour Ballroom C, Convention Level, Westin Harbour Castle
    Chair: Eve Tsai, Canada
    • S17.01: Optimizing the extracellular matrix for neural stem cell-based regeneration in traumatic spinal cord injury - Chris Ahuja, Canada
    • S17.02: Can we bioengineering a human spinal cord repair based on rats? - Eve C. Tsai, Canada
    • S17.03: Bioengineering scaffolds for cell transplantation after spinal cord injury - Shelly Sakiyama-Elbert, United States
    • S17.04: Self-assembling peptides (QL-6) or physical training foster NPC treatment in cervical spinal cord injury - Klaus Zweckberger, Germany
  • 16:30 - 18:00

    S18 - Scientific Session: Minding the 3R's: Maximizing Use and Quality of Data in Preclinical SCI Research

    Location: Pier 2+3, Convention Level, Westin Harbour Castle
    Chair: Lyn Jakeman, United States
    • S18.01: Lyn Jakeman, United States
    • S18.02: Recycle- Resources and tools to enable new knowledge from open data - Adam Ferguson, United States
    • S18.03: Reuse- Challenges and opportunities in harmonizing legacy data - Jessica Nielson, United States
    • S18.04: Reduce- Developing laboratory processes to facilitate data sharing - David Magnuson, United States
    • S.18.05: Join the movement!  - Current status of ODC-SCI - Abel Torres-Espin

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